Thyroid hormones are naturally synthesized in our body, but since the molecules are not complex, many pharmaceutical companies make the synthetic variety of the hormones. There are two basic types of thyroid hormones- T4 known as levothyroxine and T3 known as liothyronine. Both are manufactured and stored in the thyroid gland. Thyroid hormone from the pharmaceutical companies are obtained in 2 ways.- either derived from animal thyroid gland (bovine or ovine sources) or made synthetic. In the USA, the content and quantity of iodine in the thyroid preparation is well regulated. Cytomel (liothyronine sodium) is available both as a tablet or the salt of a naturally occuring thyroid hormone. T3 is many times more potent that T4 Pharmacology How thyroid hormones actually work is not really known but their actions involve myriad biochemical changes in the cells. The thyroid hormones generally provide energy to the individual. They increase the consumption of body carbohydrates, lipids and proteins, plus they enhance oxygen consumption. Individuals who take thyroid hormone generally have a higher basal metabolic rate. The thyroid hormones affect almost every organ in the body including the brain. One can only appreciate the importance of thyroid hormone when one observes patients who are deficient in the hormone. Dosing Thyroid hormone is easily absorbed from the stomach into the blood stream. The onset of action is quite rapid and usually occurs in a few hours. The peak activity of the hormone, however, may take several days. The thyroid hormone usually stays in the body for a few days after a single administration. One of the reasons why the thyroid hormone stays in the body for a few days is that in the blood it binds to albumin and is protected from breakdown by the liver.
Manufacturer: Hubei, China
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